Exfoliative Dermatitis and Toxic Hepatitis Associated with Occupational Exposure to Trichloroethylene

Hong Jae Chae; Seong Kwan Lee; Kang Jin Lee; Jong Youl Kim; Seung Chul Lee; Dong Hyeon Shin; Jai Dong Moon

doi:10.35371/kjoem.2003.15.1.111

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Case Report Exfoliative Dermatitis and Toxic Hepatitis Associated with Occupational Exposure to Trichloroethylene: Hong Jae Chae, Seong Kwan Lee, Kang Jin Lee, Jong Youl Kim, Seung Chul Lee, Dong Hyeon Shin, Jai Dong Moon; Korean Journal of Occupational and Environmental Medicine (대한직업환경의학회지) 2003;15(1):111.
DOI: https://doi.org/10.35371/kjoem.2003.15.1.111
Published online: March 31, 2003

¹Department of Occupational and Environmental Medicine, Chonnam National University Hospital, Korea. ajdmoon@chollian.net
²Department of Dermatology, Chonnam National University Hospital, Korea.
³Department of Internal Medicine, Chonnam National University Hospital, Korea.

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Abstract

A 28-year-old male began working as a degreaser. The solvent used in the degreasing operation was trichloroethylene. Over the next month the man experienced fever, chills, and an erythematous skin rash and itching. At that time he had a marked elevation in his liver enzyme, with cholestasis. Over the next few days the rash persisted then peeled. There was an elevation of Ig E, and a positive patch test reaction to trichloroethylene. His dermatitis and hepatitis were considered to be mediated by a hypersensitivity mechanism.

Keywords: Trichloroethylene;Hepatitis;Exfoliative dermatitis

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